Gender differences in the prevalence of these major psychiatric illnesses were also present (Tables 2 and 3). Among subjects without a maternal history of alcoholism or without a paternal history of alcoholism, comparisons across gender indicated similar patterns: female gender was associated with a higher prevalence of any mood disorder and any anxiety disorder. Within these categories, female gender was associated with major depression, dysthymia and each one of the specific anxiety disorders. Male gender was associated with a higher prevalence of any axis I disorder and any axis II disorder. Within the Axis I disorders, male gender was associated with conduct disorder, and pathological gambling, and any substance use disorder, and within this cluster, men were more likely than women to report each substance use disorder assessed. Within the personality disorders, men were more likely to report a cluster B personality disorder, particularly antisocial personality disorder.