have a high flexibility and can adapt to very subtle differences between neuronal trajectories (Fetz, 2007; Logothetis and Pauls, 1995; Poggio and Edelman, 1990). These examples indicate that extracting useful information from temporally evolving neuronal trajectories of long series of assemblies by statistical means may be a more formidable task than separating different neuronal trajectories by the response patterns of reader-decoder mechanisms (Laurent 1999)20 because of their ability to drastically reduce the dimensionality of information streams (Nessler et al., 2010).