Each of six overweight-obese controls with cardiovascular disease (CTR 5, 7, 10, 11, 14, 26) were compared to the best-matched three cases from a group of six normal-overweight control cases with no history of cardiovascular disease (CTR 12, 23, 27, 30, 31, 32), as indicated in Table S1. Microarrays were processed at the same time for these and the drug abuse cases. GAP scores are included for transcripts selected for the drug abuse cases ( Table 3 , Table S2 ).