The above measures suggest that the failure of LTP consolidation in the Baf53b+/− het mice and BAF53ΔHDlow groups cannot be attributed to presynaptic variables. We therefore examined the magnitude and within train facilitation of the post-synaptic responses to theta bursts in these two groups; this analysis uncovered no differences between the two genotypes and wildtype slices (Supplemental FigS4B&C). It thus appears that the loss of LTP in the mutants involves factors that operate after induction and initial expression of potentiation, a conclusion that accords with the above observation that STP is unaffected in these animals (see Fig. 5A, B, C).
