Annual incidence of hard coronary events per 1000 participants was 5.63 (95% confidence interval 4.69 to 6.69) in Belfast and 2.78 (95% CI 2.41 to 3.20) in the French centres. Annual incidence of angina was 5.46 (95% CI 4.53 to 6.54) and 3.49 (95% CI 3.06 to 3.96) per 1000 participants, respectively.