Comparisons between the three-level DSM-IV and the four-level DSM-5 diagnoses showed clear patterns of correspondence between a dependence diagnosis under DSM-IV and a severe SUD diagnosis under DSM-5. For alcohol, cocaine, and opioids, the rates of severe DSM-5 SUD among individuals with a DSM-IV dependence diagnosis were 85%, 91%, and 98%, respectively. For cannabis, 67% of subjects with a DSM-IV dependence diagnosis met criteria for a DSM-5 severe SUD, with 28% meeting criteria for a DSM-5 moderate SUD.
