Chunk #5 — METHODS — Replication study subjects, genotyping and analysis

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Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.

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Parents of UC GWAS and replication sample cases with available DNA samples were also genotyped, and affected offspring trios were analyzed using the transmission/disequilibrium test15 (see Supplementary Table 1 online).