The outcomes were diagnoses of 40 widely accepted AD30 in the index person and in relatives of an index person identified in the NPR (listed in Supplementary Table 1, together with their corresponding ICD codes). Additional analyses were conducted on specific AD that were most prevalent in the NPR and had sufficient number of observations for analysis (>10 affected individuals). Many of the ICD codes for individual AD in the NPR have been subject of validation studies and found to have high validity.29, 32, 33
