Chunk #13 — 2. METHODS — 2.5. General substance dependence analyses

Source

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.

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Logistic regression was used to estimate the effect of rs1799971 on general substance dependence with covariates for sex and age. Of the 25 available datasets, 20 had at least five cases (dependent at least one of the five substances) and five controls (no known substance dependence diagnoses and exposed to alcohol) for analysis of general substance dependence.