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Chunk #25 — Results — Hypothesis 3: associations between EXT PGS and P3 — Adolescents

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Examining associations between genetic and neural risk for externalizing behaviors in adolescence and early adulthood.
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Among EA and AA adolescents, the EXT PGS was not significantly associated with P3 amplitude (βEA = −0.04, 95% CI −0.11 to 0.03; βAA = −0.01, 95% CI −0.12 to 0.11; Table 3, Fig. 1c). There was not a significant main effect of sex for either ancestry group (βEA = 0.04, 95% CI −0.03 to 0.11; βAA = 0.05, 95% CI −0.05 to 0.14; Table 3), nor was there a significant sex by EXT PGS interaction (βEA = −0.04, 95% CI −0.11 to 0.03; βAA = −0.07, 95% CI −0.18 to 0.01; online Supplementary Table 4)