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Chunk #29 — Discussion — Relationship to activity in the theta band

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Current source density measures of electroencephalographic alpha predict antidepressant treatment response.
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not supported in analyses (Section S3 in the Supplement). Moreover, both low-alpha/theta and high-alpha were required to reliably differentiate between responders and nonresponders. Conventional EEG analysis did show a reduction in anterior-to-posterior gradient of condition-dependent theta power in nonresponders (Section S5 in the Supplement). We conclude that the observed group differences in the low-alpha/theta factor do not reflect theta, or midline frontal theta in particular, but rather are specific to classic posterior alpha.