analysis of family data in Walters et al., 2018 (Walters et al., 2018); see also Kranzler et al., 2019 that used converted genotypes (Kranzler et al., 2019)). All genotype and imputed variants with missing rates <20%, MAF ≥1% and HWE p values >0.000001 were used in analyses. 15,464,468 and 7,823,558 variants passed QC and were included in the AA and EA subsamples analyses, respectively. All variants were mapped to NCBI GRCh37.