were tissue specific, including the frontal cortex, anterior cingulate cortex, hypothalamus, and hippocampus. These results prioritize genes and brain regions for investigating how schizophrenia liability genes are expressed and influence brain activity on a systems level. Expression analysis further implicated immune system genes IL1RL1 and IL18R1 with altered expression in putamen and hippocampus, which highlights the role of immune system genes on brain functioning (Arion et al., 2007; Latiano et al., 2013). These genes specifically targeted subcortical structures, which in turn may influence cortical brain activity as measured with scalp‐recorded EEG.
