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Chunk #14 — Methods — Measures — Alcohol Use Disorder Symptoms.

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Principal Component Analysis Reduces Collider Bias in Polygenic Score Effect Size Estimation.
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Maximum lifetime alcohol use disorder criterion count in any interview (AUD Sx) were assessed based on Diagnostic and Statistical Manual of Mental Disorder (5th edition; American Psychiatric Association, 2013) using the reliable and validated SSAGA or adolescent version of the SSAGA interviews (Bucholz et al., 1994; Hesselbrock et al., 1999; Kuperman et al., 2013).