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Chunk #8 — MATERIALS AND METHODS — Participants — BN affected relative pair study

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Association study of 182 candidate genes in anorexia nervosa.
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The sample for this study included probands and affected relatives. Probands met the following criteria: (1) DSM-IV diagnosis of BN—purging type, with the additional requirement of at least a 6-month period of binge eating and vomiting at least twice a week; and (2) ages 13 to 65. Affected relatives were defined as biological family members who were (1) between the ages of 13 and 65 years, and (2) had a lifetime eating disorder diagnoses of modified DSM-IV AN (i.e., amenorrhea not required), DSM-IV BN—purging type or non-purging type, or eating disorder not otherwise specified EDNOS as defined above. For the complete list of inclusion and exclusion criteria for pro-bands and relatives, see Kaye et al. [2004].