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Chunk #20 — RESULTS — Twin Models

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Anorexia Nervosa, Major Depression, and Suicide Attempts: Shared Genetic Factors.
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Table 2 presents the results for the full (Model I) and best-fitting (Model III) models. Results from the full model show that genetic factors account for 38% (95% CI: 8%, 53%) of the liability to AN, 44% (95% CI: 24%, 50%) of the liability to MDD, and 58% (95% CI: 8%, 78%) of the liability to SA. Unique environmental factors account for most of the remaining liability. The genetic correlations suggest some sharing of genetic risk factors: ra=.49 for AN with MDD, ra=.52 for AN with SA, and ra=.77 for MDD with SA. All correlations in the full model have wide confidence intervals, indicating a lack of power to obtain precise estimates. Genetic and unique environmental parameter estimates for the best-fitting model were similar to those obtained from the full model.