DNAs were assessed in pools since this: 1) provided us with the maximal ability to protect the genetic confidentiality of subjects who volunteered for study of genetics of illegal behaviors, 2) allowed us to utilize DNAs from individuals who consented to participation in this study during time periods when consents did not explicitly describe studies using high densities of DNA markers, 3) allowed us to utilize DNAs from individuals whose consents explicitly committed us to use DNA pooling methods wherever possible to maximize protection of their genetic confidentiality, 4) allowed us to use methods that we have developed and validated in this and in previous work and 5) reduced costs. Most of these subjects would thus not have been available for studies that assessed substantial numbers of polymorphisms using individual genotyping.
