The Genome Browser website offers several tools for visualizing and analyzing genome sequences and annotation tracks. Both BLAT (13) and the in silico PCR tool quickly map sequences to genomes. The LiftOver utility translates genomic coordinates between assemblies and is available in a web interface version (at http://genome.ucsc.edu/cgi-bin/hgLiftOver) and as a command-line executable program (from http://hgdownload.cse.ucsc.edu/admin/exe/). The Table Browser (14) provides a graphical interface for retrieving, filtering, intersecting, correlating and summarizing data from Genome Browser database tables. The Gene Sorter (15) allows for exploration of gene relationships by several metrics, such as expression profiles and protein homology, and displays many types of data for each gene. Protein sequence properties are displayed as tracks and histograms in the Proteome Browser (16). VisiGene (17) displays a large collection of Xenopus and mouse in situ images that show gene expression patterns. The custom tracks tool allows the upload of user data as tracks in the browser for visualization in the context of other annotation tracks and for manipulation with the Table Browser. Custom tracks and configuration settings can be saved and shared with