correlated. The new diagnostic criteria robustly index familial risk, fulfilling a critical validator of psychiatric illnesses (Robins and Guze, 1970). However, this is true of the DSM-IV criteria as well. Future analyses could be aimed at clarifying diagnosis-specific genetic influences, and could be informed by shifts in criteria endorsement (e.g., “new” cases frequently endorse “loss of control” and “trying to cut down”: might such symptoms be influenced by genes of a particular biological function?).
