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Chunk #9 — 2 Methods — 2.1 LD Hub database — GWAS summary-level data

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LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.
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As shown in Figure 2, after filtering on the selection criteria, genome-wide results for 173 traits were included in LD Hub, of which 18 are GWAS of diseases (Boraska et al., 2014; Cross-Disorder Group of the Psychiatric Genomics Consortium, 2013; Lambert et al., 2013; Liu et al 2015; Moffatt et al., 2007; Morris et al., 2012; Neale et al., 2010; Nikpay et al., 2015; Okada et al., 2013; Paternoster et al., 2015; Ripke et al., 2012; Ripke et al., 2014; Simon-Sanchez et al., 2009; Sklar et al., 2011), 48 are medically relevant risk factors/complex traits (Benyamin et al., 2013; Berndt et al., 2013; Bradfield et al., 2012; Dastani et al., 2012; de Moor et al., 2010; Dupuis et al., 2010; Estrada et al., 2012; Furberg et al., 2010; Horikoshi et al., 2012; Huffman et al., 2015; Lango Allen et al., 2010; Manning et al. 2012; Moffatt et al., 2007; Pattaro et al., 2016; Perry et al., 2014; Rietveld et al., 2014; Rietveld et al., 2013; Saxena et al., 2010; Shungin et al., 2015; Soranzo et al., 2010; Speliotes et al.,