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Chunk #68 — Results — Scenario B — Detecting minor allele copies at rare SNPs

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A flexible and accurate genotype imputation method for the next generation of genome-wide association studies.
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Putting these pieces together, it appears that IMPUTE v2 achieves higher accuracy than other methods at rare SNPs because it has both high sensitivity and high specificity for detecting rare alleles. These results show the strength of using a large reference panel for imputation, and of our particular approach to performing inference in that setting.