To further test the specificity of this association, we predicted the strength of opto effect across subjects using a linear regression with a set of parameters from the RL model as predictors: the model-based weight (Gmb), model-free weight (Gmf), motor-level model-free weight (Gmo), and motor-perseveration strength (Pm). Model-based weight predicted the strength of opto effect on the transition predictor (p = 0.03), but none of the other parameters did (p > 0.45). These data, and an additional analysis further ruling out motor-level effects (Figure S7B), support the interpretation that inhibiting ACC blocked the influence of the state-transition on subsequent choice by disrupting model-based RL.
