The results also raise a number of possible targets for functional studies. Among SNPs within 50 kb of lead SNPs, 127 of them are identified by the fine-mapping tool CAVIARBF23 as likely causal SNPs (posterior probability > 0.9) (Supplementary Table 10). Eight of these are non-synonymous, and one of these (rs61734410) is located in CACNA1H (Supplementary Figure 9), which encodes the pore-forming subunit of a voltage-gated calcium channel that has been implicated in the trafficking of NMDA-type glutamate receptors24.
