Table 2 depicts the rate of alcohol-related events, per 100 days, stratified by OUD medication exposure and by recent AUD claims. In general, event rates were lower for buprenorphine or methadone treatment days than for days when patients were treated with either naltrexone formulation or for nonmedication days. For nontreatment days, 0.22% of days overall (mean, 535.0 days per person), 0.25% of days for those with active AUD claims (mean, 534.6 days per person), and 0.18% of days among those without active AUD claims (mean, 535.6 days per person) were marked by alcohol-related acute events. For antagonist medications, 0.29% (mean, 15.7 days per person) of oral naltrexone treatment days (0.28% [mean, 8.2 days per person] for those with active AUD claims and 0.29% [mean, 21.5 days per person] for those without active AUD claims) and 0.19% (mean, 6.4 days per person) of extended-release naltrexone treatment days (0.20% [mean, 7.5 days per person] for those with AUD claims and 0.18% [mean, 5.1 days per person] for those without AUD claims) were marked by events. Among agonist medications, 0.11% (mean, 8.4 days
