Chunk #41 — Results — Neural activity patterns in populations of mPFC neurons reflect the intention to drink in Wistar, but not P, rats

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Encoding of the Intent to Drink Alcohol by the Prefrontal Cortex Is Blunted in Rats with a Family History of Excessive Drinking.

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0.05; Fig. 6A). Thus, in P rats, the mPFC was biased toward encoding alcohol drinking during alcohol consumption, whereas in Wistar rats, encoding of the intention to drink alcohol and alcohol drinking was present. Therefore, converging evidence suggests that the encoding of alcohol drinking intent is impaired in the mPFC of P rats, which may contribute to the predisposition for excessive alcohol consumption.