To assess motor strength, WT and KO mice (n = 12) were trained to grip and hang onto a taut wire suspended 50 cm above the bench top. Training was considered complete when each animal maintained grip on the wire for 60 seconds on two occasions. The following day, all animals were injected with 2 g/kg ethanol and their ability to hang from the wire, as measured by latency to fall, was recorded prior to and at 20, 40 and 60 minutes post-injection.
