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Chunk #39 — Discussion — Internalizing symptoms predict transitions to severe AUD, but not other alcohol transitions

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Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations.
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more strongly than with initiation or quantity/frequency measures (Dick et al., 2014). Suicidal ideation has been cross-sectionally linked to more severe problematic alcohol use (Crossin et al., 2022), and suicide attempt has been longitudinally linked to future DSM-IV alcohol dependence in the COGA prospective cohort (Agrawal et al., 2017); present findings suggest that in a high-risk sample, suicidal ideation may escalate progression of AUD.