Chunk #4 — Methods — Multi-cohort data collection — Penn - University of Pennsylvania Brain Bank of Psychiatric illnesses and Alzheimer’s Disease Core Center
Brain specimens are obtained from the Penn Alzheimer’s Disease Core Center prospective collection. Disease diagnoses are made based on DSM-IV criteria and obtained through a clinical interview by psychiatrist and review of medical records. All procedures for Penn are approved by the Committee on Studies Involving Human Beings of the University of Pennsylvania, and the use of control postmortem tissues was considered exempted research in accordance with CFR 46.101 (b), item 65 of Federal regulations and University policy.