The third, most diverse 1000 Genomes reference panel used all 14 available populations from the February 2012 release of 1000 Genomes (YRI, CEU, ASW, LWK, FIN, GBR, IBS, TSI, Columbians [CLM, N = 60], Mexican Americans [MXL, N = 66], Puerto Ricans [PUR, N = 55], Northern Chinese [CHB, N = 97], Southern Chinese [CHS, N = 100], and Japanese [JPT, N = 89]). This “cosmopolitan” approach of using all available reference populations has been advocated by others, particularly for diverse study populations [2], [5], [17], [23].
