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Chunk #35 — 4. Discussion — 4.3. Evidence of both generalized and specific liabilities to addiction

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Developmental epidemiology of drug use and abuse in adolescence and young adulthood: Evidence of generalized risk.
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dependence, but also increased the odds of developing abuse or dependence on alcohol and marijuana in young adulthood. This finding was consistent with that of Bonomo and colleagues (2004) who also found an increased risk for alcohol dependence among tobacco users in adolescence using a community sample. Like previous studies (Brook et al., 1999; DeWit et al., 2000; Duncan et al., 1997; Gil et al., 2004; Grant and Dawson, 1997; Grant et al., 2006), adolescent use of alcohol and marijuana predicted both substance-specific and generalized substance problems in late adolescence/young adulthood. Likewise, the association between any tobacco use and marijuana use problems was similar to the findings of Lewinsohn et al. (1999). However, we did not replicate the association between marijuana involvement and tobacco dependence observed in Timberlake et al. (2007) possibly because of differences in the criteria for repeated-use between their study and our own. The evidence also suggests that the risk of alcohol, tobacco, and marijuana problems in young adulthood was greater if persons were diagnosed with a SUD on another substance in adolescence. Most importantly, the comparison of the adjusted versus the non-adjusted odds-ratio indicated that the associations are substantially influenced by involvement with other substances, providing