Chunk #37 — Online Methods — Stratified LD score regression

Source: Partitioning heritability by functional annotation using genome-wide association summary statistics.
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(3)E[χj2]=N∑cτcℓ(j,c)+1, whereχ2j is the marginal association test statistic at SNP j, N is the sample size and ℓ(j,c):=∑k∈Ccrjk2. An extension of this derivation to case-control traits is in Bulik-Sullivan et al. [45].