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Chunk #0 — Introduction

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Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
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Smoking is associated with many different diseases. Lung cancer is the illness most identified with smoking, and its prevalence over time mirrors per capita tobacco consumption [1]. There has been a reduction in smoking in the United States, and a concomitant decline in the incidence of lung cancer is beginning to emerge. Nonetheless more people die from lung cancer each year than from any other cancer [2]. Chronic obstructive pulmonary disease (COPD), another serious lung disease largely attributable to smoking, is also among the leading causes of death.