Chunk #16 — Results — Characterization of PPRE transgenic mice

Source

Assessment of chitosan-affected metabolic response by peroxisome proliferator-activated receptor bioluminescent imaging-guided transcriptomic analysis.

Embedded

yes

Text

Plasmid DNA pGL-PPRE5x-Ptk was selected for the generation of transgenic mice following pronuclear microinjection of FVB oocytes. Because the transgene contained a luciferase gene driven by PPRE, the luciferase activity reflected the PPAR trans-activity.