Chunk #56 — Online Methods — 1. Data matrix, primary analysis and processing, quality control — 1.2 ChIP-seq and DNase-seq uniform reprocessing for consolidated epigenomes — d. Genome-wide signal coverage tracks
(1) Fold-enrichment ratio of ChIP-seq or DNase counts relative to expected background counts λlocal. These scores provide a direct measure of the effect size of enrichment at any base in the genome. (2) negative log10 of the Poisson p-value of ChIP-seq or DNase counts relative to expected background counts λlocal. These signal confidence scores provides a measure of statistical significance of the observed enrichment.
