Chunk #51 — METHODS — Gene-based association and tissue-specific gene expression.

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Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.

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We used MAGMA v1.08 implemented in FUMA v1.3.6a23 to perform gene-based association analysis using the full summary statistics from the GWAS meta-analysis. Genome-wide significance was assessed through Bonferroni correction for the number of genes tested (P = 0.05/18381 = 2.72 × 10−6).