Applications of hiPSCs for investigating AUDs are still in their nascent stage, but promising results have been obtained from several hiPSC models of neuropsychiatric disease, including schizophrenia (Toyoshima et al. 2016; Brennand et al. 2015; Lin et al. 2016), bipolar disorder (Mertens et al., 2015b; Stern et al., 2017), and Alzheimer’s disease (Liao et al., 2016; Mahairaki et al., 2014; Yang et al., 2016). Although hiPSC models have been applied to a large number of different types of neurological disorders, we focus here on a polygenic subset.
