Twin studies suggest that there are genetic effects on P3 electrophysiological measures obtained in target detection tasks during adolescent development (Katsanis et al., 1997; van Beijsterveldt et al., 1998, 2001; Carlson and Iacono, 2006). As mentioned above, effects of SNPs from CHRM2 (Jones et al., 2006b), GRM8 (Chen et al., 2009), CRHR1 (Chen et al., 2010), HTR7 (Zlojutro et al., 2011), and KCNJ6 (Kang et al., 2012) on P3 related electrophysiological measures in adults have been documented. One study found an effect of CHRM2 SNPs on P3 electrophysiological measures in children and young adolescents (Hill et al., 2013).
