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Chunk #40 — Discussion — Using the MEP for biochemical analysis of populations at their median RLS

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Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae.
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median life span we found that ERC levels in fob1Δ cells actually increase significantly as cells approach their median RLS, although their accumulation was reduced/delayed compared to wild type cells. The extension of our ability to observe age-associated genetic and biochemical changes with the MEP allows us to begin to develop an understanding of the order of events that affect an aging population.