change of deaths, age-standardised death rates, DALYs, and age-standardised DALY rates between 2006 and 2016, for all risk-outcome pairs, both sexes combinedRisk2006 deaths (in thousands)2016 deaths (in thousands)Percentage change of deaths 2006–16Percentage change of age-standardised deaths rate 2006–162006 DALYs (in thousands)2016 DALYs (in thousands)Percentage change of DALYs 2006–16Percentage change of age-standardised DALYs rate 2006–160All risk factors: all causes31 848·45 (31 122·54 to 32 552·54)32 756·24 (31 855·63 to 33 694·29)2·85 (1·12 to 4·76)*–18·73 (−20·03 to −17·34)*1 182 311·16 (1 130 619·01 to 1 237 965·11)1 080 115·72 (1 017 412·55 to 1 149 380·02)–8·64 (−10·66 to −6·56)*–21·71 (−23·29 to −20·02)*1Environmental and occupational risks: all causes9751·57 (9103·89 to 10 482·39)9293·43 (8663·33 to 9987·21)–4·70 (−7·01 to −2·37)*–24·30 (−26·04 to −22·49)*367 198·64 (341 616·82 to 392 521·03)311 970·97 (290 297·06 to 335 402·79)–15·04 (−18·03 to −12·10)*–27·23 (−29·61 to −24·99)*2Unsafe water, sanitation, and handwashing: all causes2231·21 (1736·49 to 3001·11)1660·77 (1253·69 to 2312·04)–25·57 (−32·82 to −16·38)*–36·78 (−42·78 to −29·05)*118 178·24 (99 042·42 to 141 176·50)75 796·04 (61 906·38 to 93 460·54)–35·86 (−41·64 to −29·70)*–40·76 (−45·87 to −35·67)*3Unsafe water source: all causes1570·53 (716·65 to 2364·77)1160·16 (515·93 to 1858·37)–26·13 (−34·62 to −15·83)*–37·49 (−44·89 to −28·82)*82 040·06 (38 265·29 to 110 406·22)52 440·65 (23 552·84 to 73 900·44)–36·08