Chunk #35 — Results — Identification of trans effects and conditioned co-expression analysis

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Complex nature of SNP genotype effects on gene expression in primary human leucocytes.

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Subsequently, we redid this co-expression analysis after having removed the genotypic effect on the probe intensity level for the probes that constitute the significant cis-eQTLs (Figure 4b). We observed a considerably increased number of significantly correlated transcript-pairs: 54,773 (an increase of 7.8%) and 258,874 (an increase of 53.8%), respectively.