While interview participants encountered important challenges related to the TD team science approach, they also described how they were ultimately successful in using the approach. They identified four key facilitating factors and strategies for success at the levels of the individual team members, team, research center, and TREC I initiative. These were: (1) beneficial attitudes and beliefs about TD research and team science among participating investigators;(2) effective team processes; (3) brokering and bridge-building activities by individuals holding particular roles in a research center; and (4) funding initiative characteristics that supported TD research and team collaboration.
