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Chunk #85 — Online Methods — eQTL Analysis

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Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder.
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Expression quantitative trait loci (eQTL) analysis was performed for all SNPs in each cell type within 100,000 bases of a differentially expressed gene overlapping a GWAS loci and within an ATAC-seq peak from that cell type. tensorQTL106 was used to perform the analysis using the map_cis function with default parameters. Variants with minor allele frequency < 0.05 were excluded from the analysis. Sex, age, and ethnic origin were used as covariates.