Fibroblast biopsies were obtained from healthy controls that were recruited as part of a longitudinal study by Dr. Judith Rapoport (NIMH)73. All participants provided written assent/consent with written informed consent from a parent or legal guardian for minors. Human fibroblasts (HFs) were cultured on plates coated with 0.1% gelatin (in milli-Q water) and grown in HF media (DMEM (Invitrogen), 20% FBS (Gemini)).