In addition, we selected six quantitative traits—height (HGT), body mass index (BMI), high-density lipoproteins (HDL), low-density lipoproteins (LDL), cholesterol (CHOL), and triglycerides (TRIG)—that have been measured in the Partners Biobank healthy control population with a Charlson age-comorbidity index 0–2 and the predicted 10-year survival probability greater than 90%. We predicted these quantitative traits in a relatively heathy population to avoid measurements affected by severe diseases or medications. For participants that have multiple measurements of a trait of interest, we used the median value. Table 1 presents the sample size for each curated disease and quantitative trait in the Partners Biobank.
