52 monozygotic twin pairs, identified by IBD (preferentially retaining cases), and 7 individuals who matched samples from the Psychiatric Genomics Consortium, identified using genotype checksums24. After imputation, individuals with missingness ≥ 2%, and genotype with a call rate of ≤98%, MAF ≤ 0.5% and HWE P-value ≤ 1E-05 were excluded using PLINK version 1.9.25,26. Strand ambiguous SNPs with 40% ≤ MAF ≤ 50% were also excluded.