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Chunk #21 — 5. Fibroblasts as the Common First Choice

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A Comparative View on Human Somatic Cell Sources for iPSC Generation.
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Alternatively, fibroblasts are commercially available from several companies. Meanwhile, human fibroblasts from various organs and tissues of the body are available, for example, dermal [46], cardiac (ventricle or atrium) [47], lung [48], or periodontal ligament fibroblasts [49]. Even cells from patients who suffer from different diseases are available such as fibroblasts isolated from lung tissue of asthma patients, chronic obstructive pulmonary disease, or cystic fibrosis [50]. However, fibroblasts from donors with rare and exotic diseases are hardly available.