Informed by previous studies in these data, we tested differences in trajectories of alcohol, marijuana, and tobacco use among Black and White participants in the Add Health sample. We examine differences in quantity and frequency of alcohol, tobacco, and marijuana use between Black and White respondents from adolescence (mean age 16) through adulthood (mean age 29), stratified by gender, robustly testing modification of association with race/ethnicity by survey wave, and fully adjusting for multiple measures of socio-economic position to comprehensively investigate the evidence for convergence and/or cross-over of risk among Black and White participants during the transition to adulthood.