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Chunk #2 — Background

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Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients.
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We aimed to investigate the possible involvement of dopaminergic polymorphisms in the etiology of impulsive self- and other-damaging behaviors (assessed by borderline and antisocial traits) in a previously studied US community-based sample of 99 young adults from low-to-moderate income families [13]. This group could be regarded as an at-risk population, because it has been shown that low family socioeconomic status confers a risk for BPD [14] and low educational or occupational status is an important risk factor for suicide attempts [15]. In this sample 4% were diagnosed with BPD and 7% with antisocial personality disorder (APD) in young adulthood, showing a prevalence 2-3 times higher compared to the general community (BPD: 1-2%, APD: 2-3%) [16,17]. A group of 136 Hungarian patients with mood disorder served as the replication sample for findings related to borderline traits, because borderline diagnosis, as well as borderline traits, have a high prevalence rate among psychiatric inpatients (15%) [16].