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Chunk #17 — Methods — Statistical analyses

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A genetic perspective on the proposed inclusion of cannabis withdrawal in DSM-5.
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Using the cross-twin cross-trait correlations, we also partitioned the covariance between cannabis withdrawal and abuse/dependence into its additive genetic, shared environmental and nonshared environmental sources in the same way as we did for the variance in cannabis withdrawal. We calculated the genetic correlation, a measure of the overlap in the genetic variation underlying cannabis withdrawal and abuse/dependence. Further, we partitioned genetic and environmental influences on cannabis withdrawal into those that were shared with abuse/dependence and those that were unique for cannabis withdrawal.