cessation processes such as natural vs. assisted cessation. A larger study or meta-analysis is required to examine the effect of different pharmacotherapies in the combined genetic risk groups. Many other genes have been nominated as predictive of smoking cessation (34), and we anticipate more genes will be identified as playing a role in smoking cessation. Risk prediction modeling to incorporate multiple genetic markers and non-genetic predictors will lay the foundation for a personalized treatment algorithm (35).
